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Why is my dose of warfarin higher (or lower) than that of other people I know?

April 26, 2017dose lower people warfarin

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Why is my dose of warfarin higher (or lower) than that of other people I know?

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The dose of warfarin required by different people to maintain a therapeutic protime is influenced by their height, their weight, their dietary intake, other medications that are being taken and by genetic factors that influence the metabolism of the drug. Specifically the genetic factors include CYP2C9 and VKORC1.