Why is my 40mg Adderall XR not working anymore?
Adderall XR and Zoloft can interact and cause symptoms such as poor concentration and restlessness. Let your doctor know that the increased dose in Adderall is not working. Biologically speaking, both drugs help produce serotonin in the brain, so since you are on both at the same time, you may be getting a little too much serotonin. You can see if the doctor can prescribe Prozac or Effexor instead of Zoloft, although there is a chance they will still cause the same symptoms.