Why is mixing methadone with other drugs especially dangerous?
Methadone reduces heart-rate and respiration, and even a small amount of alcohol or other medications can suppress respiration and heart-rate to deadly levels. Someone not aware of this interaction will overdose and die. Many people don’t know that drugs such as a diuretics (water pills); certain antibiotics, some heart or blood pressure medications, HIV medications, some MAO inhibitors, other narcotic medications such as Subutex, or seizure medication can cause a deadly affect when mixed with small amounts of Methadone. Additionally, as it’s use as a pain medication is relatively new, doctors who prescribe it for pain relief are not as experienced as those who prescribe it in the clinics.
