Why is intrathecal baclofen preferred over oral baclofen?
Baclofen can be taken orally or delivered into the intrathecal space. The intrathecal space contains the cerebrospinal fluid, the fluid surrounding the spinal cord and nerve roots. Oral baclofen causes side effects that might limit its usefulness. Of the oral baclofen delivered throughout the body, only a small portion goes to the spinal fluid where it is needed to work. An intrathecal delivery system, which provides the baclofen right to the target site in the spinal cord, is an effective way to deliver the medicine.
