Why is infectious mononucleosis important as it relates to Hodgkin’s disease?
Several studies have shown an association between Hodgkin’s disease and a prior diagnosis of infectious mononucleosis. This association appears primarily among young adult patients (all MDPH interview participants were young adults when diagnosed). A recent study found a three-fold increased risk of Hodgkin’s disease in young adults with a prior diagnosis of infectious mononucleosis. 18. What did the biological tissue analyses of the MDPH participants show? The results of blood and tissue block analyses showed a pattern consistent with the literature and also similar to that seen in the HSPH comparison group, again indicating that the MDPH participants were not unusual in terms of what has been measured among a larger group of young adults from the Greater Boston area diagnosed with Hodgkin’s disease. The cell type of Hodgkin’s disease and indicators of immune responses to the presence of EBV were similar in the MDPH group as the scientific literature indicates for young adults diagnos
