Why is diabetes and hyperglycemia a Risperdal side effect?
Hyperglycemia associated with diabetic ketoacidosis has been reported in patients treated with atypical antipsychotics, including Risperdal. Diabetic ketoacidosis or DKA is a condition where the body has a severe deficiency of insulin. Assessment of the relationship between atypical antipsychotic use and glucose abnormalities is complicated by the possibility of an increased background risk of diabetes mellitus in patients with schizophrenia and the increasing incidence of diabetes mellitus in the general population. The relationship between Risperdal and hyperglycemia-related adverse events is not completely understood. However, studies suggest an increased risk of treatment-emergent hyperglycemia-related adverse side effects in patients treated with Risperdal.