Why is Creatine Supplementation Important in Sports Nutrition?
During rapid muscle contraction PCr stores get depleted resulting in the reduction of capacity of ATP resynthesis, and thereby energy production8. It is assumed that an increase in total muscle Cr concentration would limit the depletion of the PCr stores during intense muscular exercise and the decline in the ATP resynthesis rate by increasing the ADP phosphorylation rate. The potential benefits of this mechanism on exercise performance have been evoked to justify the administration of oral Cr to competitive athletes11. Creatine is slowly but continuously converted to creatinine, which itself is no use to the muscle for energy production and eventually excreted in the urine. As a result creatine must be continuously resupplied from indigenously or through the diet, if a metabolic demands of the muscles are to be maintained. Currently, creatine does not appear on the International Olympic Committee (IOC) banned substances list because it is naturally occuring constituent of a normal die
