Important Notice: Our web hosting provider recently started charging us for additional visits, which was unexpected. In response, we're seeking donations. Depending on the situation, we may explore different monetization options for our Community and Expert Contributors. It's crucial to provide more returns for their expertise and offer more Expert Validated Answers or AI Validated Answers. Learn more about our hosting issue here.
As vaults are highly conserved throughout eukaryotic evolution and abundantly expressed in all cells, it is likely that they will not be immunogenic. Like viruses, vaults self assemble and have a large internal cavity. If vaults can be engineered to contain exogenous materials (proteins, nucleic acids, drugs etc.). they may be suitable for use as delivery vehicles.
