Why does the Report page sometimes show a difference between the Genetic Distance and the number of mismatches?
Genetic Distance is a measurement that does not take into consideration mismatches that are a result of single events. ADNATiP™ uses the infinite allele model as opposed to the stepwise model, and that’s why, for example, a two step mutation in a single marker is considered one mismatch even though it will read as a Genetic Distance of 2. 9. A group of us have been working to confirm the genetic signature of a specific line. I used the ADNA TiP calculator to calculate the probable amount of time to their common ancestor. Next, I increased the number of generations to 7. As expected, the results changed. However, our question to you….. Why did the probability become less when we eliminated the possibility of a common ancestor within the past 7 generations? It seems that it should increase? Remember, we are talking cumulative probabilities. That’s the key to understanding something that initially seems counter intuitive. Let’s use an example for a specific situation of one mismatch in
Genetic Distance is a measurement that does not take into consideration mismatches that are a result of single events. FTDNATiP™ uses the infinite allele model as opposed to the stepwise model, and that’s why, for example, a two step mutation in a single marker is considered one mismatch even though it will read as a Genetic Distance of 2.
Related Questions
- I have understood the copying limitations outlined on page 3. Does this affect my obligation to report performances or other utilisations in any way?
- Why does the Report page sometimes show a difference between the Genetic Distance and the number of mismatches?
- Appendix 4 of the results report shows the raw data sorted by genetic distance. What is genetic distance?
