Why does the immune system of sarc patient seems to be in a loop and cannot get rid of these bugs?
These CWD bacteria have learned to live inside the actual macrophages (phagocytes) of the immune system. These CWD bacteria fail to be destroyed by the very cells (phagocytes) which are supposed to kill them, as they have learnt to live in the caustic ‘cytokine soup’ inside a granuloma. The control of 1,25-D (which regulates the “hospitality” your immune system extends to these bugs) is the area of genetic predisposition to sarcodiosis, IMO.