Why does the creatinine clearance from the APK© program differ from what I calculate by hand?
The difference is most likely due to the weight that you are using in your hand calculation. Because creatinine is produced by muscle tissue, C&G; recommend that you use lean body weight, except in morbidly obese patients. Because creatinine is produced by muscle tissue, not fat, additional weight in form of fat does not significantly alter the production of creatinine. There is considerable difference of opinion among practitioners concerning the most appropriate creatinine clearance equation to use.
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