Why does hypothyroidism cause brittle hair, oedema round the eyes and a husky voice?
The 3 and the 4 relate to the number of iodine molecules in each thyroid hormone molecule. Up to 80% of the T4 is converted to T3 by peripheral organs such as the liver, kidney and spleen. T3 is about ten times more active than T4 Once it has been released by the thyroid the T3 & T4 travel through the bloodstream, with the purpose of helping cells convert oxygen and calories into energy to serve as the basic fuel of your metabolism As T3 (the biologically active hormone) circulates through your bloodstream it attaches to and enters your cells via receptor sites on the cell membrane. Once inside the cells T3 increases the cell metabolic rate including body temperature and stimulates the cells to produce a number of different hormones, enzymes, neurotransmitters and muscle tissue. T3 also helps your cells use oxygen and release carbon dioxide; this in turn helps to provide a smooth metabolic function. T3 affects practically every cell in the body, and therefore is a powerful orchestrator
