Why do you now recommend using Cefoxitin 10 g discs in place of methicillin discs for the detection of methicillin resistance?
A. Cefoxitin is a good inducer of PBP 2a and consequently performs much better than methicillin in the detection of heterogeneous and low level resistance. All mecA gene positive Staphylococcus aureus examined have had a cefoxitin zone of < 6 mm in annular radius, mitigating the need to look for resistant colonies within the zone of inhibition.
Related Questions
- In cases where the detection voltage of the power supply is greater than 10V, is it possible to connect a resistance between the VDD pin and the power supply?
- Why do you now recommend using Cefoxitin 10 g discs in place of methicillin discs for the detection of methicillin resistance?
- How much detection reagent do you generally recommend for LiquiChip Assays?
