Why do we use FAEEs and the FAEEs combined with Etg but not Etg alone to indicate alcohol abuse or abstinence over longer time periods?
Etg alone is still not practicable! FAEEs (nanogram = one billionth of a gram) appear in hair in almost one order of magnitude higher than (the relevant order of magnitude of) Etg (picogram = one trillionth of a gram). It has been technically possible to measure FAEEs since 1993, whereas the technique for measuring (the relevant range of) Etg is still in its infancy. In practice, most hair which is sent for analysis has been cosmetically treated in some way (bleached, permed etc.). It has been proven that FAEEs are not significantly affected by such treatments (Hartwig et al., 2003a). So far no similar systematic investigations have been carried out for Etg. FAEE concentrations in hair from other body sites can be interpreted in a similar fashion as scalp hair (Hartwig et al., 2003b). No similar studies have been done for Etg. Extensive studies involving over 1000 donors have been carried out since 2000. These have enabled us to establish reliable reference ranges for FAEEs with respec