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Why do the directions say to only apply LATISSE™ solution to the base of the upper eyelashes?

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Why do the directions say to only apply LATISSE™ solution to the base of the upper eyelashes?

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Clinically proved that there is potential hair growth  in areas where LATISSE solution comes in repeated contact with the skin surface. So its  important to apply LATISSE  only to the skin of the upper eyelid margin at the base of the eyelashes using  sterile applicators, and to carefully remove Latisse from other skin areas.

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A clinical trial of LATISSE™ was conducted on patients who applied the product to the base of their upper lashes only. Applied nightly, the transfer of LATISSE™ solution from the upper to lower eyelid may occur naturally because the eyelids are closed and the eyelashes touch each other. Over application may increase the chance of experiencing side effects. To ensure safety and maximize effectiveness, please follow the directions provided.

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