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Why do sometimes the CSI changes slightly when Extra Corporeal Circulation (ECC) is started?

changes CSI ECC slightly STARTED
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Why do sometimes the CSI changes slightly when Extra Corporeal Circulation (ECC) is started?

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The use of ECC changes the blood volume of the patient; hence the plasma concentration of the anaesthetic agent is changed. In consequence the effect site concentration is altered; and therefore the CSI will change accordingly.

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