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Why do I need to hand mix whole blood tubes and separate sera from the clot?

blood clot hand mix separate sera tubes
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Why do I need to hand mix whole blood tubes and separate sera from the clot?

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The EDTA or heparin in whole blood tubes does not automatically blend with the blood, so unmixed samples will still clot. When shipped during the winter or packed in ice, clots in serum tubes will hemolyze, altering test results.

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