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Why do I need a skin biopsy to diagnose small fiber sensory neuropathy?

April 26, 2017biopsy Diagnose fiber Neuropathy sensory skin small

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Why do I need a skin biopsy to diagnose small fiber sensory neuropathy?

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Small fibers travel too slow and their conduction responses cannot be captured by nerve conduction study/EMG which is a routine test performed to evaluate for large sensory and motor nerve fibers. Therefore, skin biopsy is used to evaluate small sensory nerve fibers in the skin.