Why do Depo-Provera shots stop periods?
If you’ve gotten your injections on time, the absence of periods does not mean you’re pregnant and is not something to worry about. Periods stop because Depo-Provera causes a “resting state” in the ovaries. When your ovaries do not release an egg each month, the growth of the lining of the uterus does not occur, so neither does menstrual bleeding. The medical term for this is called amenorrhea. Periods usually return within three to 10 months after you stop receiving the injections.