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Why do children with Alagille syndrome experience poor growth?

April 26, 2017alagille children experience growth poor SYNDROME

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Why do children with Alagille syndrome experience poor growth?

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We don’t fully understand why children with Alagille syndrome experience growth failure. Possible causes include insufficient calorie intake, fat malabsorption (decreased ability to absorb fat) due to liver or pancreatic disease, congenital (present at birth) defects (such as heart disease) and the defect in the Jagged1 gene.