Why Do Antioxidant Trials Fail?
No one knows the precise answer to this question. More importantly, no one doing antioxidant studies asks if supplementing antioxidants to a pro-oxidative and pro-inflammatory diet is a reasonable way to assess antioxidant efficacy. Atherosclerosis and diabetes are now known to be inflammatory diseases.8 Insulin insensitivity is thought to be a promoter of both diabetes and atherosclerosis: “Evidence at present favors chronic inflammation as a trigger for chronic insulin insensitivity, rather than the reverse situation.”9 Those of us trained in manual care tend to view inflammation as an outcome of cell damage; the dead cells cause acute inflammation. However, living cells perpetuate inflammation, and the best way to turn our bodies into inflammation-producing machines is to eat the typical American diet: “The highly processed, calorie-dense, nutrient-depleted diet favored in the current American culture frequently leads to exaggerated supraphysiological post-prandial spikes in blood g