Why do acne scar creams have such a low rate of effectiveness?
The explanation may very well emerge from understanding that the skin matrix is responsible for the skin’s mechanical properties, including firmness, strength, suppleness, and elasticity. Acne scars are injuries in a skin matrix affected by atrophy, a condition characterized by exactly the contrary of those just mentioned. Yes, skin affected by acne scars is characterized by weakness, thinning, roughness, sagging, stiffness, and decrease in the size of tissues, diminished cellular proliferation, and decreased function, also called atrophia. The skin matrix is a precious resource which is both produced and consumed quite frequently during our lives. On one hand, skin matrix is continuously synthesized by fibroblasts. On the other hand, whenever it is damaged, malformed or worn out, skin matrix -particularly the structural proteins collagen and elastin- is broken down into fragments by collagenase and gelatinase enzymes, also called matrix metalloproteinases (MMP) and then recycled. By d
