Why did I get negative result for A. phagocytophilum on my SNAP 4Dx Test and the reference lab got a positive result on an IFA test?
• An IFA test is a highly subjective read and may cross-react with other species of Anaplasma and Ehrlichia. It is possible to have an acute infection where the IFA test is detecting a mixture of antibody responses to various organisms that may or may not be Anaplasma phagocytophilum. • The SNAP 4Dx Test uses a highly specific immunodominant peptide from the A. phagocytophilum organism. • Alternatively, if the infection truly is A. phagocytophilum, the host may require additional time to mount an immune response to the particular epitope that is detectable on the SNAP 4Dx Test. • If you suspect A. phagocytophilum infection, but the SNAP 4Dx Test is negative, it is recommended to retest the animal in one to three weeks. Please keep in mind that the clinical signs of A. phagocytophilum closely resemble those of Lyme disease and E. canis infection.
Related Questions
- One of my crewmembers tested positive, but he got some counseling and took another test and came up negative. Can I put him back to work on my boats?
- Why did I get negative result for A. phagocytophilum on my SNAP 4Dx Test and the reference lab got a positive result on an IFA test?
- Why did I get a positive A. phagocytophilum result on my SNAP 4Dx Test and a negative test result at the reference lab?
