Why did Biotivia Choose Not to Include Quercetin?
We have devoted quite a bit of study and research to quercetin’s effect on resveratrol and resveratrol’s metabolites and the issue of Sirt 1 activation. Our conclusion is that the most recent and best designed studies, including a study by one company that actually puts quercetin in their product, conclude that quercetin strongly inhibits the metabolites of resveratrol and suppresses SirT1 activation. Quercetin has been shown in numerous studies to interfere with the beneficial metabolites of resveratrol. These metabolites, particularly resveratrol glucuronide, resveratrol sulphate and picead possess important health properties. Studies also confirm that enterohepatic recirculation (recirculation by the liver) of these metabolites contributes significantly to the enhanced exposure of resveratrol in the tissues of mammals. Furthermore, quercetin’s undesirable Sirt 1 suppression clearly rules it out as an ingredient in any longevity product. If Biotivia scientists believed that quercetin
