Why did BD develop BD APC-H7 tandem conjugates?
The increased spillover into the APC channel due to APC-cyanine tandem degradation has been a challenge for some customers needing to keep experimental samples exposed to room temperatures or paraformaldehyde-based fixatives for any extended period of time. This spillover reduced sensitivity in the APC channel and resulted in insufficient resolution and increased experimental variability in this and other nearby channels. To address this problem, BD Biosciences engineered an APC-cyanine with enhanced stability and performance in these situations.
