Why combination treatment in Systemic hypertension?
Majority of patients of hypertension will require more than one drug for the control of blood pressure (BP) to the desired level. The combination therapy has many advantages. 1. In combination treatment, lower dose of each drug can achieve good BP control with very little or no side effects. 2. All patients do not respond to same drugs and hence combination treatment is more effective. 3. Combination medications can be synergestic in BP reduction. 4. The drugs with varying modes of action can result in longer and smoother control of BP. 5. In properly selected drug combinations side effects of one can be neutralized by the other. 6. Combination therapy is more organ protective because of smooth blood pressure control. 7. Blood pressure reduction to target levels can be achieved more frequently. 8. Cost of treatment can be brought down by accepted fixed dose combinations, 9. Less frequent administration along with lower side effects leads to better patient compliance to combination medi
