Why can alternatives such as computer models and cell cultures replace animal research?
Computer models and cell cultures, as well as other adjunct research methods, are excellent avenues for reducing the number of animals used. These methods are used to screen and determine the toxic potential of a substance in the early stages of investigation, thereby reducing the total number of research animals needed. The final test, however, has to be done in a whole, living system. Even the most sophisticated technology cannot mimic the complicated interactions among cells, tissues and organs that occur in humans and animals. Scientists must understand these interactions before introducing a new treatment or substance into humans. In addition, there are very strong economic incentives to replace animals with computers or other adjunct methods. Research animals are very expensive to acquire and care for and are only used because no alternatives currently exist. For the near future, however, these adjunct technologies will be used in conjunction with, not instead of, laboratory anim