Why cannot some bodies digest simple sugars like sucrose?
Sucrose is a disaccharide, composed of glucose and fructose. You need an enzyme to break it down. Disaccharide Intolerance Type I (Mendelian Inheritance in Man database: *222900) is a rare inborn error of metabolism resulting from mutation in sucrase-isomaltase (Enzyme Catalog 3.2.1.48). Usually, infants with SI deficiency come to attention because of chronic diarrhea and nutritional evidence of malabsorption.
