Why aren’t carriers of other prostate cancer predisposition genes being targeted?
Previous published research has suggested that these two genes are linked to an increased risk of prostate cancer. In some populations there have been reports that alterations in other genes may predispose to prostate cancer. These leads will be looked at in other populations to determine if they confer an increased risk in other countries. At the moment IMPACT is recruiting carriers of alterations in BRCA1 and BRCA2 but in other countries other gene alteration carriers may be included as these data are published.
