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Why are there discrepancies regarding time line information for boosters of Typhim Vi and Oral Typhoid?

April 26, 2017boosters discrepancies line oral time typhim typhoid Vi

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Why are there discrepancies regarding time line information for boosters of Typhim Vi and Oral Typhoid?

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Recommendations regarding Typhoid vaccines are inconsistent. For example, the Berna and CDC websites suggest that a booster following a 4-dose schedule of Vivotif be administered after four years (http://www.bernaproducts.com/PDFs/Vivotif2004PIL.pdf and http://www.cdc.gov/ncidod/dbmd/diseaseinfo/typhoidfever_g.htm#Getting%20vaccinated). Others suggest a booster at seven years following a 3-dose schedule (RXMed.com). The CDC website recommends a booster at 2 years following Typhim Vi (http://www.cdc.gov/ncidod/dbmd/diseaseinfo/typhoidfever_g.htm#Getting%20vaccinated ). A position paper by OMS recommends a booster at 3 years for both vaccines ( referring to 3-dose initial schedule for oral typhoid) – http://www.who.int/docstore/wer/pdf/2000/wer7532.