Why are there different estimated levels of GFR for African Americans?
The MDRD study equation includes a term for the African American race to account for the fact that African Americans have a higher GFR than Caucasians (and other races included in the MDRD Study) at the same level of serum creatinine. This is due to higher average muscle mass and creatinine generation rate in African Americans. Clinical laboratories may not collect data on race and therefore may report GFR estimates using the equation for Caucasians. For African Americans, multiply the GFR estimate for Caucasians by 1.21.