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Why are the drug levels in oral fluid levels so low?

April 26, 2017drug fluid levels low oral

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Why are the drug levels in oral fluid levels so low?

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Oral fluid drug levels tend to correlate with blood levels of the drug (dependent on the Saliva/Plasma ratio for each drug). Urine generally contains excreted drug metabolites. The body concentrates these metabolites in the urine and therefore urine drug levels are much higher.