Important Notice: Our web hosting provider recently started charging us for additional visits, which was unexpected. In response, we're seeking donations. Depending on the situation, we may explore different monetization options for our Community and Expert Contributors. It's crucial to provide more returns for their expertise and offer more Expert Validated Answers or AI Validated Answers. Learn more about our hosting issue here.

Why are some modified oligos so expensive in relation to the cost of the modifying reagent?

April 26, 2017COST expensive modified modifying oligos Reagent relation

0

Posted

Why are some modified oligos so expensive in relation to the cost of the modifying reagent?

1 Answer

0

Posted

The limited reagent stability (most <48 hours) and lower coupling efficiencies of the reagent requires that excess modifying reagent be used to insure adequate quantities of full length product is made. As a result, higher cost incurred in synthesis.