Why are NCI and NHGRI pursuing the characterization of the human cancer genome now?
The Human Genome Project provided a model for approaching large-scale biomedical research projects. The experience and technological advances resulting from the Human Genome Project have made it feasible to consider large-scale science projects. While conceptually feasible, a large-scale cancer genomic characterization project will require new research into cancer biology as well as additional technological improvements. To demonstrate the practicality of this approach, a pilot project will be a very important first step. The pilot project will drive development of more cost-effective and efficient technologies that will be needed to examine cancer genomes in sufficient detail. Genomics, along with the development of advanced imaging methods, nanotechnology, new drug discovery and development, improved biomarkers and proteins, and extensive clinical research, potentially will change the way cancers are prevented, diagnosed and treated.
