Why are Iodosorb* and Iodoflex* contraindicated with thyroid disease?
Iodine is important in the synthesis of the thyroid hormones, T3 (triiodothyronine) and T4 (thyroxine). In normal healthy individuals a reduction in plasma iodide concentration will result in decreased hormone production and an increase in thyroid stimulating hormone, whereas an increase in plasma iodide concentration has the opposite effect. Iodine given orally in high doses may transiently reduce thyroid hormone secretion. With iodine containing products such as Iodoflex and Iodosorb there is some systemic absorption of iodine. Therefore reduction in thyroid stimulating hormone will exacerbate already low levels of the thyroid hormone in those with hypothyroid diseases, such as Hashimoto’s Thyroiditis and non – toxic nodular goitre.
