Why are calico cats always female?
Calico cats are not always female, but the vast majority of them are. If a male cat is calico, it is usually sterile because it’s a genetic defect for the cat. XXY, a three chromosome cat. Calico means that there are 3 colors present. The colors in a cat are a sex-linked trait. The third color comes from the X-chromosome and that comes from the female have XX when the male only has one X.