Who Needs to Be Tested for Inheritance of the MEN 1 Gene?
People with a family history of MEN 1 as well as those individuals in whom illness may be related to MEN 1 require tests to determine if they have inherited the MEN 1 gene. How Is Inheritance of the MEN 1 Gene Diagnosed? The most reliable way to determine if MEN 1 gene has been inherited is to do a genetic test (predictive genetic testing). Recent advances have made it possible to perform predictive genetic testing at any age. This requires only a single blood sample. The DNA in the blood sample is analyzed for the presence of an abnormal MEN 1 gene. People with an abnormal MEN 1 gene are said to have a positive result. This test can detect MEN 1 even when all other tests are normal. A negative genetic test result means that a person does not have MEN 1, nor can they pass MEN 1 to their children. Those individuals with a positive genetic test result should have regular tests for endocrine gland over-activity. Genetic testing is not usually part of routine MEN 1 blood testing. If you wo