Who is not a good candidate for PDE-5 inhibitors?
PDE5 inhibitors aren’t suitable for everyone. Those taking nitrate drugs for angina should never take any of the PDE-5 inhibitors. Men with the following conditions should talk with their primary care doctors before taking any of the ED drugs. • Severe heart disease, such as unstable angina, a history of heart attack, or arrhythmias. Sildenafil increases nerve activity associated with cardiovascular function, especially during physical and mental stress. Men with heart disease may benefit from an exercise test to determine whether resuming sexual activity increases their risk of a heart attack. • Recent history of stroke. • Hypotension (very low blood pressure). • Uncontrolled diabetes. • Uncontrolled hypertension. • Taking anticoagulant therapy. • Severe heart failure. • Retinitis pigmentosa.