Who Is At Risk of Beta Thalassemia?
Beta thalassemia is inherited. This means that the beta globin genes are passed from parent to child. There are 2 genes total. Problems with one or both genes can lead to different types of beta thalassemia including: • Beta thalassemia minor (also called beta thalassemia trait). This type occurs when only one gene is affected. It may cause mild anemia. • Beta thalassemia intermedia. This type can occur when both genes are involved. It is likely to cause anemia in early childhood. It may also cause other problems such as an enlarged spleen or liver. • Beta thalassemia major (also called Cooley’s anemia). This type can also occur when both genes are involved. It is the most severe type of beta thalassemia. It is likely to cause severe anemia that requires blood transfusions. It can also cause problems with organs such as the liver, spleen, heart, and bones. Parents and siblings of a child with beta thalassemia should be tested for the condition too. A genetic counselor can answer questi
