Who gets Polycystic kidney disease?
Autosomal Dominant (ADPKD), the most common type of PKD, doesn’t skip a generation and usually occurs in those with family history. A parent with ADPKD has 50 percent chance of passing down the disease to the next generation, no matter how many children a person has. In some families, all children are affected; in some others, non are. There are both affected and unaffected children in most families.
In few cases of Polycystic Kidney Disease, there is no family history of the disease and the gene coding for the disease occurs out of a spontaneous genetic mutation without either parent being a carrier of the gene.
Autosomal recessive (ARPKD) requires a mutated gene from each of the parents for the disease to be manifested in a child. ARPKD is a rarely seen type of PKD.
