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Who gets osteonecrosis?

osteonecrosis
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Who gets osteonecrosis?

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Osteonecrosis has several causes. In fact, most osteonecrosis is found in people who have not had cancer. In the general population, risk factors for developing osteonecrosis include the following: • Sickle cell disease • Injury to the bone through fracture or dislocation • Excessive alcohol use • Long-term corticosteroids for both non-cancer and cancer diseases Among individuals with a history of cancer, corticosteroid therapy is considered the major risk factor for the development of osteonecrosis. Survivors with a history of acute lymphoblastic leukemia (ALL) and various types of lymphoma represent most of the individuals who previously received corticosteroid therapy. Previous studies have estimated that somewhere between 1.7 and 7.9% of acute lymphoblastic leukemia (ALL) survivors develop osteonecrosis in the first 3-5 years after diagnosis. Among ALL patients who receive corticosteroid therapy, the following patient characteristics are particularly associated with an increased ri

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