Who develops Hemolytic Uremic Syndrome?
Approximately one in every 10 children who have E.coli 0157:H7 gastroenteritis will go on to develop Hemolytic Uremic Syndrome. HUS is caused by the effect of toxins produced by the E.coli bacteria on the body’s circulation, affecting red blood cells, the kidneys, and in some cases, the brain. HUS is usually diagnosed between the eighth and twelfth day of the diarrheal illness, although many children have developed HUS earlier. The disease is most common in children less than 5 years of age. What are the symptoms and implications associated with HUS? Symptoms of HUS include extreme irritability and fatigue, paleness of the skin, and a decrease in urine output. Children must be watched very carefully for signs of illness. Usually associated with a lengthy hospital stay, at least 80% of children who develop HUS will require multiple blood transfusions, and approximately 50% will need dialysis. How can parents help prevent E.coli 0157:H7 gastroenteritis and HUS? The following are recommen
