Important Notice: Our web hosting provider recently started charging us for additional visits, which was unexpected. In response, we're seeking donations. Depending on the situation, we may explore different monetization options for our Community and Expert Contributors. It's crucial to provide more returns for their expertise and offer more Expert Validated Answers or AI Validated Answers. Learn more about our hosting issue here.

Which type of oligodeoxynucleotides (ODNs) can be transfected with jetPEI™?

April 26, 2017jetpei™ transfected type

0

Posted

Which type of oligodeoxynucleotides (ODNs) can be transfected with jetPEI™?

1 Answer

0

Posted

jetPEI™ successfully transfects regular phosphodiester ODN as well as any partially or fully modified phosphorothioate ODN. It has been shown to form stable complexes with ODNs protecting them from enzymatic degradation. However, jetPEI™ is unable to complex with neutral ODN such as PNA (peptides nucleic acid) or fully modified methylphosphonate.