Which statement is NOT true about DNA replication?
A. is true, because DNA polymerase III cannot synthesize in the 3’→5′ direction, the lagging strand is synthesized in short segments known as Okazaki fragments. B. is true due to the fact that it must replicate from 5′ to 3′. To do this (on the lagging strand), it creates the Okazaki fragments (replicates bit by bit rather than continually) in order to accomplish the 5′ to 3′ concept. C. is FALSE D. is true because most bacteria have a single circular chromosome that can range in size from only 160,000 base pairs in the endosymbiotic bacteria meaning there isnt much difficulty in replicating its DNA. E is true becuase it must begin at the origin of replication (also called the replication origin) which must be recognized by the Origin Recognition Complex (ORC). Origins contain DNA sequences recognized by replication initiator proteins (ORC) which in turn recruit other proteins (helicase, polymerase…) to separate the two strands and initiate replication forks. The ANSWER is C. This is
