Which rare side effects have occured so far?
If the sensitivity to temperature is restricted, there may happen undetected overheatings during local or regional hyperthermia. This can happen with tumors that have already been treated preliminarily, i.e. after extended operations and after radiation etc. In such cases, there may occur damages of the tissue, respectively necroses after hyperthermia. It is possible, however, to detect these risk groups by detailed pre-examinations and the actual rate of such incidents is under 1 % at the experienced centers. In some rare cases, it may happen that the patient cannot stand being positioned in the ring-shaped applicator during one hour or more, due to claustrophobia (anxiety caused by narrow spaces). This problem can be checked beforehand by a so-called trial positioning. It may be useful to administer sedatives in this case. Sometimes (but rarely) it is not possible to apply hyperthermia in case of a claustrophobia. As to the whole-body hyperthermia, the possible risks consist in the h
