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Which of the following statements related to acute chest syndrome in sickle cell anemia is correct?

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Which of the following statements related to acute chest syndrome in sickle cell anemia is correct?

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bronchodilators have no role in the acute treatment. b) most common chest x-ray finding is new infiltrate in bilateral upper lobes. c) only exchange transfusion provides benefit. d) pulmonary infection is rarely the inciting cause. e) transfusion of packed red blood cells can significantly improve the patient’s condition. A) Studies suggest that patients with sickle cell disease have increased airway reactivity. In addition to this, increased airway reactivity further compounds the problem of sickle cell anemia secondary to hypoxia. With this in mind, it is recommended inhaled beta agonist therapy be administered in all patients whom may have acute chest syndrome, even those with no wheezing. B) The most common x-ray finding in acute chest syndrome is bilateral lower lobe infiltrates. D) In a large multicenter study it was found through bronchoalveolar lavage the second most common inciting event of acute chest syndrome is infection. Most commonly Chlamydia pneumoniae followed by Mycop

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