Which of the following smallpox vaccination strategies is most likely to have the best risk/benefit ratio?
A. National mass vaccination program B. Ring vaccination and containment C. Vaccination of immediate family only D. Vaccination of the index cases Answer 8. A 38-year-old woman is evaluated in the emergency department because of fever and a generalized rash. She was in her usual state of good health until seven days ago. At that time, she rapidly developed a high fever, headache, backache, chills and abdominal pain with occasional vomiting. Four days ago she developed a rash. It started as a red, flat rash, then evolved into small papules, and now consists entirely of vesicles. She takes no medications. She recalls having chickenpox as a child. On physical examination, her temperature is 104 F (40 C), blood pressure is 148/90 mm Hg and pulse is 112/minute. She appears acutely ill and is possibly confused. She has a generalized vesicular eruption on her face, extremities (including the palms and soles), thorax and abdomen. The vesicles are well circumscribed, round and firm to palpation
