Which mutation is more severe, point mutation or frameshift mutation?
It really depends on the exact mutation itself. As you probably know, a mutation can be positive, negative, or neutral. Most of the time, mutations are negative unfortunately. A Frame Shift mutation is when nucleotides are removed or sometimes added. As you may know, nucleotides make our DNA. Every three nucleotides make up a ‘codon’. A codon codes for a specific amino acid. A series of codons together code for a series of amino acids which together make a specific protein. Let me give you a practical example. one boy ate pie (oneboyatepie) – pretend that sentence is my DNA coding. Each letter is a nucleotide, every three make up a codon that codes for a specific amino acid and all together a protein. The simple message that piece of DNA gives is that one boy ate pie. If a frame shift mutation was to occur to that piece of DNA the following could happen. The sentence that was once known as oneboyatepie could turn into eboyatepie. The O and N were deleted. When we put this piece of DNA
