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Which is better for my protein separation, TSKgel PW or SW columns?

April 26, 2017columns protein pw Separation SW tskgel

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Which is better for my protein separation, TSKgel PW or SW columns?

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In general, TSKgel SWxl columns provide better resolution for protein separations than TSKgel PWxl columns because of the higher pore volume of the silica-based SWxl packing material than the polymer-based PWxl packing material in high buffer and high salt concentration mobile phases. Although TSKgel PWxl and PW columns are ideally suited for analysis of water-soluble synthetic polymers, when it comes to biopolymers we only recommend PWxl columns for high pH applications (>7.5) or for viruses and DNA fragments.