Important Notice: Our web hosting provider recently started charging us for additional visits, which was unexpected. In response, we're seeking donations. Depending on the situation, we may explore different monetization options for our Community and Expert Contributors. It's crucial to provide more returns for their expertise and offer more Expert Validated Answers or AI Validated Answers. Learn more about our hosting issue here.

Which drugs reduce the effect of coumarin derivatives (VKAs)?

April 26, 2017coumarin derivatives drugs reduce

0

Posted

Which drugs reduce the effect of coumarin derivatives (VKAs)?

1 Answer

0

Posted

Reducing the effect means: thrombophilia increases, INR drops, Quick value rises: • Anti-epileptics (e.g. Carbamazepin, barbiturates) • Antimycotic drugs (e.g. Griseofulvin) • Antituberculous drugs (e.g. Rifampicin) • Vitamin preparations (vitamin K) • Laxatives are to be assessed with care because the effect on anticoagulation is not predictable This list is not comprehensive! Only the most common drug classes and drugs are indicated.